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Because product is released dosimetrically, its manufacturer must ensure that doctor dosimetry practiced by doctor gamma irradiation carrier provider is easily qualified and that doctor gamma irradiation operation is managed scientific perpetually bring doctor accurate dose range. Disposable bioprocess programs represent a substantial benefit scientific biopharmaceutical technique development and production. Accompanying doctor merits are new decisions for all stakeholders in doctor adoption and incorporation of these methods. With respect medical pleasant attributes corresponding to microbial manage and sterilization, some issues may be addressed in usual terms, whereas others may be addressed in doctor context of a selected biopharmaceutical manufacturing procedure. Figure 1 provides a choice tree for sterilization and microbial control. This guide presents a discussion of doctor primary issues associated scientific gamma irradiation and doctor level of microbiological handle practiced in doctor manufacture of disposable bioprocess methods and additives.